One problem at a time please 
Enabling SecureBoot will break the Nvidia drivers again (until we understand why that happened). In my view SecureBoot adds only false security, so leaving it disabled is not a big deal.
Do NOT use opi codecs, it is known for causing problems and you already have some interesting ones 
You might be good to go without Packman or you might just need a few packages from that, see for instance this thread.
Adding zram might or might not help performance (and which performance?) but please don’t clutter this thread with unrelated problems.
Back to the original problem, check what the following command writes out now that the Nvidia drivers are apparently working:
systemctl status asusd power-profiles-daemon supergfxd
You may also check which processes are actually using which GPU with nvtop (zypper in nvtop if you don’t find it) and what is going on with the Nvidia GPU with nvidia-smi.