Rufus Boot Configuration

What are the recommended configurations for *Rufus *when creating a USB Boot Drive?
Through looking at previous threads I see that DD Image Mode is recommended, but nothing else about the other options, like Partition Scheme, Target System, or File System. The wiki as well is out of date with the current version of Rufus on its instructions and image.

I’m not a “rufus” user (because I’m not a Windows person). But I think that if you use DD mode, then the other options are not relevant (they probably don’t do anything).
Settings are greyed out.

An alternate app would be
I think there is an app image