I am facing the same problem.
Starting ifolder from a console windows give the following messages:
user@linux86_x64:~> ifolder
Error: Cannot start the local web services.
Error: The Simias process failed to initialize.
Use the command line switch --showconsole to view the error.
Unhandled Exception: System.NullReferenceException: Object reference not set to an instance of an object
at Novell.iFolder.iFolderApplication.StartiFolder () [0x00000] in <filename unknown>:0
at System.Threading.Thread.StartUnsafe () [0x00000] in <filename unknown>:0
[ERROR] FATAL UNHANDLED EXCEPTION: System.NullReferenceException: Object reference not set to an instance of an object
at Novell.iFolder.iFolderApplication.StartiFolder () [0x00000] in <filename unknown>:0
at System.Threading.Thread.StartUnsafe () [0x00000] in <filename unknown>:0
Starting ifolder with the option --showconsole does not give any additional information.
after some debugging with strace I found that you need to install the package mono-wcf (version mono-wcf-2.10.6-2.1.3.x86_64 on my machine).
I needed to reboot then ifolder worked fine on my system.