I seem to keep getting this error quite a bit, here is an example:
glxinfo
name of display: :0
libGL error: dlopen /usr/lib64/dri/updates/radeonsi_dri.so failed (/usr/lib64/dri/updates/radeonsi_dri.so: cannot open shared object file: No such file or directory)
Are you using the radeon or the fglrx driver?
The Mesa package includes /usr/lib64/dri/radeonsi_dri.so, so it should not matter that /usr/lib64/dri/updates/radeonsi_dri.so is not there (actually it shouldn’t even be there).
Which version do you have installed?
Oh, and specifying which openSUSE version and graphics card you are using would be a good idea as well. 
Opensuse Factory, AMD Radeon 270x
OpenGL vendor string: X.Org
OpenGL renderer string: Gallium 0.4 on AMD PITCAIRN
OpenGL core profile version string: 3.1 (Core Profile) Mesa 10.1.0
OpenGL core profile shading language version string: 1.40
I believe the issue I am having is the libgl error:
glxgears
libGL error: dlopen /usr/lib64/dri/updates/radeonsi_dri.so failed (/usr/lib64/dri/updates/radeonsi_dri.so: cannot open shared object file: No such file or directory)
So it is Factory, not 13.2 Milestone0, right?
OpenGL vendor string: X.Org
OpenGL renderer string: Gallium 0.4 on AMD PITCAIRN
OpenGL core profile version string: 3.1 (Core Profile) Mesa 10.1.0
OpenGL core profile shading language version string: 1.40
OK, so that’s the radeon driver.
I believe the issue I am having is the libgl error:
glxgears
libGL error: dlopen /usr/lib64/dri/updates/radeonsi_dri.so failed (/usr/lib64/dri/updates/radeonsi_dri.so: cannot open shared object file: No such file or directory)
As I said, Mesa does contain radeonsi_dri.so, in /usr/lib64/dri/. Do you have that?
That it isn’t found in /usr/lib64/dri/updates/ should not matter, that directory is just for overriding stuff in /usr/lib64/dri/.
/usr/lib64/dri/updates/ is completely empty (except for a README file) even on my 13.1 system.
That message is just debug output, it is not the cause of your issue.
What exactly is your issue, btw?
If it’s just this message, ignore it.
I just tried the latest Factory KDE LiveCD (timestamped April 1st, it contains Mesa-10.1.0), glxinfo (and OpenGL) works fine on my Radeon 9600 (RV350).
I do get the same message as you (about /usr/lib64/dri/updates/r300_dri.so of course), but otherwise there are no problems AFAICT.
Just this error nothing else causing an issue.
OK, then ignore it as I said.
It is not really an error.
As Factory is the development and testing branch for the next openSUSE version (I hope you know that ), it’s not really surprising that it would have additional debug output enabled.