How can I invert only one channel of my headphone with pipewire/pavucontrol

EasyEffects might be a viable option for you? It has a Stereo Tool that allows phase inversion on a per channel basis…
https://wwmm.github.io/easyeffects/stereotools.html
Not sure about a suitable openSUSE package for Leap 15.5, but perhaps a Flatpak install would be suitable…