Having trouble with 12.1 and Radeon driver? Look here!

After installing display drivers for my HD 6450 Gnome-shell failed to start up.

The solution for me:
Go to the AMD site and download this file.
Right click it and make it executable. Run it.
Download and install the AMD drivers with YaST. I think you may have to add the repository below.

Index of /mirror/ati/openSUSE_12.1

Next open a Terminal window and run

aticonfig --initial

Reboot.

It worked for me! rotfl!