Best (and Twitter) Linux Client

I have used Twitter a lot but I’ve discovered now and some of my friends only use that so now I’m looking around for a good client for Linux. I use several distros such as Ubuntu with Gnome and several KDE based distros (Mandriva, OpenSUSE, CentOS, Fedora).
Which are some of the best clients?
Also, are there clients that work with both and Twitter so I could just use one client?