First, welcome to the openSUSE Forums.
You may have to disable Pulse Audio and fall back to the ALSA Audio – SDB here: <https://en.opensuse.org/SDB:Pulseaudio>.
In addition, for serious Audio workplaces, the Real-time Kernel often has to be used – related Forums thread dealing with low-latency Audio here: <https://forums.opensuse.org/t/lowest-possible-realtime-midi-to-sound-latency/138054>.