Application locked just means there’s another instance of an updater running - if the updater applet is running, you can’t open YaST software management, for example, for understandable reasons. Most errors of the ‘content’ kind have been transitory, in my experience. You could try a different mirror if you’re desperate, but I wouldn’t worry about it unless it lasts several days. although I admit that it’s suspicious that it happens with every repo)