I run two monitors of different resolutions on an nVIDIA 6600, as two separate X screens. You might find my (edited for space) xorg.conf useful.
Code:
Section "ServerLayout"
Identifier "Layout[all]"
Screen 0 "Screen0" 0 0
Screen 1 "Screen1" RightOf "Screen0"
InputDevice "Keyboard[0]" "CoreKeyboard"
InputDevice "Mouse[1]" "CorePointer"
Option "Clone" "off"
Option "Xinerama" "off"
EndSection
Section "Files"
InputDevices "/dev/gpmdata"
InputDevices "/dev/input/mice"
FontPath "/usr/share/fonts/misc:unscaled"
<snip>
EndSection
Section "Module"
Load "glx"
Load "type1"
Load "extmod"
Load "dbe"
Load "freetype"
EndSection
Section "ServerFlags"
Option "AllowMouseOpenFail" "on"
Option "ZapWarning" "on"
Option "Xinerama" "0"
EndSection
Section "InputDevice"
Identifier "Keyboard[0]"
Driver "kbd"
Option "Protocol" "Standard"
Option "XkbLayout" "us"
Option "XkbModel" "microsoftpro"
Option "XkbRules" "xfree86"
EndSection
Section "InputDevice"
Identifier "Mouse[1]"
Driver "mouse"
Option "Buttons" "7"
Option "Device" "/dev/input/mice"
Option "Name" "Microsoft IntelliMouse Optical"
Option "Protocol" "explorerps/2"
Option "Vendor" "Sysp"
Option "ZAxisMapping" "4 5"
EndSection
Section "Monitor"
Identifier "Monitor0"
VendorName "Dell"
ModelName "DELL 1704FPT"
HorizSync 30.0 - 81.0
VertRefresh 56.0 - 76.0
Option "DPMS"
Option "PreferredMode" "1280x1024"
EndSection
Section "Monitor"
Identifier "Monitor1"
VendorName "Samsung"
ModelName "SAMSUNG LE22S86BD"
HorizSync 30.0 - 81.0
VertRefresh 60.0 - 75.0
EndSection
Section "Device"
Identifier "Videocard0"
Driver "nvidia"
VendorName "NVIDIA Corporation"
BoardName "GeForce 6600"
BusID "PCI:1:0:0"
Screen 0
EndSection
Section "Device"
Identifier "Videocard1"
Driver "nvidia"
VendorName "NVIDIA Corporation"
BoardName "GeForce 6600"
BusID "PCI:1:0:0"
Screen 1
EndSection
Section "Screen"
Identifier "Screen0"
Device "Videocard0"
Monitor "Monitor0"
DefaultDepth 24
Option "TwinView" "0"
Option "TwinViewXineramaInfoOrder" "DFP-0"
Option "metamodes" "DFP: 1280x1024 +0+0"
SubSection "Display"
Depth 24
Modes "1280x1024"
EndSubSection
EndSection
Section "Screen"
Identifier "Screen1"
Device "Videocard1"
Monitor "Monitor1"
DefaultDepth 24
Option "TwinView" "0"
Option "TwinViewXineramaInfoOrder" "CRT-0"
Option "metamodes" "CRT: 1680x1050 +0+0"
EndSection
Section "Extensions"
Option "Composite" "on"
EndSection